As Ventica provides an unprecedented insight into breathing during sleep, we conducted a clinical study to understand the sources of variability in breathing flow profiles in healthy subjects. This newly published study helps in understanding the neurophysiological background of Ventica® EVI® parameter.
The main finding is that different sleep stages are the primary cause for changes in the flow profiles.
The study is published in the Respiratory Physiology & Neurobiology journal.
• First analysis of tidal breathing flow-volume curves by sleep stages.
• Curves are more similar within individual N3 cycles than in other sleep stages.
• Curves are substantially different between separate N3 cycles.
• Body position changes have lesser impact on the curves than sleep stage changes.
This article also suggests that the night to night change in sleep architecture (proportions of sleep stages) is a probable source for the night to night EVI variation that we see in non-obstructed patients (EVI in green area).
Read the whole article here